Services
Strategic Project Guidance
Scientific advisor: building program strategy for early-stage companies with proposed screens, compound library, profiling workflow, path to IP, timelines and resources
Have a great idea but need to assess project feasibility to execute on starting a program and the path to identifying a development candidate? Leveraging a vast experience across several programs in both large pharma and biotech, receive a plan for your drug discovery project with proposed timelines and resources. You will receive screening strategies proposals to identify a chemical matter starting point in a timely manner, along with an assessment of competitive landscape and a path to securing intellectual property.
Fractional head of drug discovery: elaborating strategy towards milestones, project team leadership, managing internal and external drug discovery functions, outsourced chemistry, BoD and investor presentations
Your early-stage company needs to jumpstart a drug discovery project? With fractional consulting, add an experienced medicinal chemist to your scientific leadership team and execute on your strategy with hands-on management of outsourced chemistry, compound profiling, structural biology, modelling, DMPK. Leverage a vast experience across modalities: inhibitors of kinases, PPI, covalent, molecular glues, splicing modulators, conjugates, bifunctional molecules, peptides.
Integrated drug discovery
Hands-On Medicinal Chemistry
Experienced medicinal chemist: performing hit expansion, multi-parameter optimization (potency, selectivity, ADME/PK), compound design, profiling and prioritization, data and SAR analysis, ligand-based and SBDD
Need to increase medicinal chemistry bandwidth to support a drug discovery project? With fractional consulting, add an experienced medicinal chemist to collaborate closely with your multidisciplinary drug discovery team. For Boston-based clients, have in person team meetings, live design brainstorming sessions and prioritization.
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Lead optimization
Multi-parameter optimization, SAR analysis, improving and balancing potency, selectivity and ADME/PK properties
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Innovative designs
Detailed data analysis, joint brainstorming sessions, ideas proposals
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Active CRO management
Synthesis prioritization, queue management, troubleshooting and performance improvement
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Chemoinformatic tools
Structure-based drug design (SBDD), ideation tools and AI when useful to streamline workflows.
Due diligence
Drug discovery expert: reviewing company technology, portfolio and competitive landscape, reviewing development candidate package, compound library
Need an expert advice before committing to a project or investing in a company? Receive a detailed assessment of project, technology, portfolio or patent applications, with interactive review meetings, complete data review, landscape analysis, SWOT analysis, suggested timelines and resources.
MapleSeed was founded by Benoit Moreau, PhD in 2025 to help early-stage companies, biotech and CROs with their needs in drug discovery. Benoit worked for over 17 years as a medicinal chemist and scientific leader in pharma and biotech, successfully initiating drug discovery programs on early platforms, working collaboratively within multi-disciplinary teams, making several key design contributions and leading project teams to the identification of development candidates across multiple therapeutic areas. He has built strong internal medicinal chemistry teams and managed efficiently large external chemistry teams at CROs in Asia, North America and Europe.
Get support to plan your drug discovery projects or to supplement your current team